Pfizer expands cost cuts with new $1.5B target

Pfizer, already in the midst of an aggressive effort to trim spending, on Wednesday disclosed new plans to cut at least $1.5 billion in additional costs over the next several years.  The program is meant to reduce what Pfizer spends on producing its medicines and will include “operational efficiencies, network structure changes and product portfolio…

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Pheon rides wave of ADC interest with $120M financing

British biotechnology startup Pheon Therapeutics has raised another $120 million in venture funding, riding a wave of investor interest in the type of cancer medicines, known as antibody-drug conjugates, it specializes in. The Series B funding, announced Tuesday and led by TCGX Capital, will help Pheon bring multiple drugs into clinical testing against solid tumors….

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Forbion-backed biotech Progentos debuts with $65M for MS drug

Forbion, a well-known backer of life sciences startups, is leading an investment round for a newly launched biotechnology company focused on diseases that affect nerve cells. The company, Progentos Therapeutics, has raised $65 million through a Series A financing that also involved Alta Partners, Mission BioCapital, Longwood Fund and Dolby Family Ventures. Progentos says the…

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Biogen, Ionis shelve ALS drug following study failure

Biogen and Ionis Pharmaceuticals are stopping development of an experimental drug for ALS following new clinical trial results that didn’t meet the companies’ expectations. The trial, which enrolled almost 100 people with the nerve-destroying disorder, found the drug actually worked as intended. Biogen and Ionis had designed it to lower levels of “ataxin-2,” a protein…

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