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In an effort to make the internet more accessible for people with disabilities, researchers at The Ohio State University have begun developing an artificial intelligence agent that could complete complex tasks on any website using simple language commands. In the three decades since it was first released into the public domain, the world wide web…

UCLA-led research finds that scooter injuries nearly tripled across the U.S. from 2016 to 2020, with a concurrent increase in severe injuries requiring orthopedic and plastic surgery over the same period. The study, which compared national trends in scooter and bicycle injuries during the period, also found that costs to treat those injuries rose five-fold,…

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment. They also found a way to deliver immunotherapy’s cancer-killing impact without the unwelcome side effect. The findings are published in Science. “This is a good example of how understanding a mechanism helps…

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as “brittle bone disease.” This small animal-based research, published today in Developmental Cell and led by members of the McKay Orthopaedic Research Laboratory of…

A new study published in the journal Diabetes demonstrates that a glucagon-like peptide-1 receptor (GLP-1R) agonist, a member of a class of medication used to treat Type 2 diabetes and obesity, can lead to a rapid improvement in insulin sensitivity. Insulin sensitivity is how responsive cells are to insulin, an essential hormone that controls blood…

In and out of the workplace, people often keep adverse information about themselves secret because they worry that others will judge them harshly. But those fears are overblown, according to new research from the McCombs School of Business. In fact, when study participants pushed through fear to reveal a secret, those in whom they confided…

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability. The sperm and egg are made during meiosis,…

Many bacterial pathogens use small injection apparatuses to manipulate the cells of their hosts, such as humans, so that they can spread throughout the body. To do this, they need to fill their syringes with the relevant injection agent. A technique that tracks the individual movement of proteins revealed how bacteria accomplish this challenging task….

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study. The variant, located in a mitochondrial microprotein dubbed SHLP2, was found to be highly protective against Parkinson’s disease; individuals with…

For people looking to start 2024 with a new routine to feel fitter and happier, a new study from the University of Bath suggests that combining mindfulness with exercise could be your key to success. A study, published in the academic journal Mental Health and Physical Activity, suggests that life changes which combine both physical…

A groundbreaking study led by Professor Sebyung Kang and Professor Sung Ho Park in the Department of Biological Sciences at UNIST has unveiled a remarkable breakthrough in cancer treatment. The research team has successfully developed unprecedented “NK cell-engaging nanodrones” capable of selectively targeting and eliminating cancer cells, offering a potential solution for intractable types of…

Through an international collaboration, scientists at St. Jude Children’s Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand. They discovered precisely which amino acids control the key pharmacological…

Antibiotic-resistant bacteria have become a rapidly growing threat to public health. Each year, they account for more than 2.8 million infections, according to the U.S. Centers for Disease Control and Prevention. Without new antibiotics, even common injuries and infections harbor the potential to become lethal. Scientists are now one step closer to eliminating that threat,…